Figure S8 from β-Adrenergic Signaling in Mice Housed at Standard Temperatures Suppresses an Effector Phenotype in CD8+ T Cells and Undermines Checkpoint Inhibitor Therapy
posted on 2023-03-31, 00:45authored byMark J. Bucsek, Guanxi Qiao, Cameron R. MacDonald, Thejaswini Giridharan, Lauren Evans, Brian Niedzwecki, Haichao Liu, Kathleen M. Kokolus, Jason W.-L. Eng, Michelle N. Messmer, Kristopher Attwood, Scott I. Abrams, Bonnie L. Hylander, Elizabeth A. Repasky
This figure shows that similar to our observations in mice treated with only propranolol, treating 4T1 tumor-bearing mice with anti-PD-1 and propranolol does not increase the frequency or relative number of CD8+ T cells in tumors.