Figure S4 from Impaired Antitumor Immune Response in <i>MYCN</i>-amplified Neuroblastoma Is Associated with Lack of CCL2 Secretion and Poor Dendritic Cell Recruitment

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posted on 2023-04-04, 01:42 authored by Jamila Kacher, Olivier Manches, Caroline Aspord, Hervé Sartelet, Laurence Chaperot

<p>Supplementary figure 4 shows flow cytometry gating strategy for cell subsets identification (migration experiments)</p>

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Etablissement Français du Sang (EFS)

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DOI - Is supplement to Impaired Antitumor Immune Response in MYCN-amplified Neuroblastoma Is Associated with Lack of CCL2 Secretion and Poor Dendritic Cell Recruitment

ARTICLE ABSTRACT

In MYCN-nonamplified neuroblastoma, CCL2 produced by neuroblastoma cells induces the recruitment of antigen-presenting cells (DCs and monocytes/macrophages), allowing infiltration by T cells, in link with CCL19 and CCL22 production, hence favoring immune responses.