Figure A3 from Expression of Five Neuroblastoma Genes in Bone Marrow or Blood of Patients with Relapsed/Refractory Neuroblastoma Provides a New Biomarker for Disease and Prognosis
posted on 2023-03-31, 20:23authored byAraz Marachelian, Judith G. Villablanca, Cathy W. Liu, Betty Liu, Fariba Goodarzian, Hollie A. Lai, Hiroyuki Shimada, Hung C. Tran, Jaime A. Parra, Richard Gallego, Nora Bedrossian, Sabrina Young, Scarlett Czarnecki, Rebekah Kennedy, Brian D. Weiss, Kelly Goldsmith, Meaghan Granger, Katherine K. Matthay, Susan Groshen, Shahab Asgharzadeh, Richard Sposto, Robert C. Seeger
Comparison of 1 year EFS in two groups defined by a range of ∆CT cut points (left column) and corresponding ROC analysis of the ability of ∆CT values above the cutpoint to predict 1 year EFS (right column), for assays based on different combinations of genes. NB5 assay (A, B), Phox2B/TH/DDC (C, D), Phox2B/TH (E, F), Phox2B/TH/Dcx (G, H), Th/Dcx (I, J). These analyses show that the NB5 assay is at least as or more predictive then the other gene combinations.