Figure 6 from Determining the N-Glycan and Collagen/Extracellular Matrix Protein Compositions in a Novel Outcome Cohort of Prostate Cancer Tissue Microarrays Using MALDI-MSI

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posted on 2024-11-27, 09:40 authored by Jordan P. Hartig, Kaitlyn Bejar, Lyndsay E.A. Young, Grace Grimsley, Jennifer R. Bethard, Dean A. Troyer, Javier Hernandez, Jennifer D. Wu, Joseph E. Ippolito, Lauren E. Ball, Jonathan A.L. Gelfond, Teresa L. Johnson-Pais, Anand S. Mehta, Robin J. Leach, Peggi M. Angel, Richard R. Drake

Analysis of collagen/ECM profile of NED vs. MET cohort from data obtained by LC-MS/MS. A, Pie chart representations of abundance (peak intensity and number of peptides identified via LC-MS/MS) of all detected protein species within the MET cohort. B, Pie chart representations of abundance of all detected protein species within the NED cohort.

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ARTICLE ABSTRACT

Using matrix-assisted laser desorption/ionization mass spectrometry imaging techniques on a unique cohort of prostate cancer tissues, we highlighted several molecular characteristics of matrix that have potential to act as early predictors of prostate cancer metastasis.