Figure 4 from Ternary Complex Components Responsible for Rapid LDL Internalization as Biomarkers for Breast Cancer Associated with Proliferation and Early Recurrence

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posted on 2025-02-04, 09:40 authored by Elizabeth S. McDonald, Tien-Chi Pan, Dhruv K. Pant, Melissa A. Troester, Andrew V. Kossenkov, David A. Mankoff, Robert H. Mach, Lewis A. Chodosh

PAM50, derived Oncotype DX, and a new proliferation score (Prolif224) were all similarly related to RFS. JRH, John Radcliffe Hospital; RFS, recurrence-free survival.

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ARTICLE ABSTRACT

This first large-scale analysis of the putative ternary complex responsible for rapid low-density lipoprotein internalization in breast cancer reveals a link between component expression and recurrence, with prognostic implications for identifying patients needing supplemental posttreatment surveillance and/or additional therapeutic approaches.