FIGURE 5 from Immunologic Assessment of Tumors from a Race-matched Military Cohort Identifies Mast Cell Depletion as a Marker of Prostate Cancer Progression

BCR-free and metastasis-free survival probabilities for cell type ratios with clinical significance. Youden index is used to stratify high versus low abundances. BCR-free survival probabilities are plotted for high and low relative cell type scores for DC (A) versus TILs, mast cells versus TILs (B), cytotoxic cells versus TILs (C), and B cells versus TILs (D) based on log-rank P < 0.05. Metastasis-free survival probabilities are shown for high and low relative cell type scores for NK cells versus TILs (E), mast cells versus TILs (F), CD8 versus exhausted CD8 (G), and Th1 versus TILs (H) based on log-rank P < 0.05.