American Association for Cancer Research
crc-23-0003_fig3.png (179.93 kB)

FIGURE 3 from Antidepressant Use and Lung Cancer Risk and Survival: A Meta-analysis of Observational Studies

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posted on 2023-06-12, 14:20 authored by Eunkyung Lee, Yongho Park, David Li, Alice Rodriguez-Fuguet, Xiaochuan Wang, Wen Cai Zhang

Forest plot showing the pooled effects of AD use on survival among lung cancer survivors. Blue square and horizontal lines represent relative risks (RR) and 95% CI for each study. The blue boxes reflect the statistical weight of the study. The dotted vertical line indicates the line of no effect. The red diamond represents the pooled RR with its 95% CI.


University of Central Florida (UCF)



In this meta-analysis of 11 observational studies, we found evidence of a statistically significant association between the use of certain ADs and lung cancer risk. This effect merits further study, particularly as it relates to known environmental and behavioral drivers of lung cancer risk, such as air pollution and cigarette smoke.