FIGURE 2 from Prediagnostic CT or MRI Utilization and Outcomes in Hepatocellular Carcinoma: SEER-Medicare Database Analysis

OS estimates by Imaging group. Comparison of OS between patients with HCC receiving different types of imaging without adjustment for lead-time bias (A) and after adjustment for lead-time bias with mean sojourn time of 6 months (B). Median OS was 20.5 months (95% CI: 19–22 months), 15 months (95% CI: 13–17 months), and 10 months (95% CI: 9–11 months) for CT/MRI, US, and no imaging, respectively without adjustment for lead-time bias. Median OS was 16.7 months (95% CI: 15.8–18.6 months) and 12 months (95% CI: 10.7–14.1 months) for CT/MRI and US, respectively, with adjustment for lead-time bias. Lead-time adjustment would not affect median OS of no imaging group. CT, computed tomography; HCC, hepatocellular carcinoma; MRI, magnetic resonance imaging; US, ultrasound.