Prognostic significance of DR categorization for patients with colorectal cancer in the two cohorts. A, Primary cohort. B, Validation cohort. HR, hazard ratio; DR, desmoplastic reaction.
Funding
MOST | NSFC | National Science Fund for Distinguished Young Scholars (National Science Foundation for Distinguished Young Scholars)
GDSTC | Special Project for Research and Development in Key areas of Guangdong Province (广东省科技计划重点领域研发项目)
广东省人民政府 | National Natural Science Foundation of China-Guangdong Joint Fund (国家自然科学基金-广东省联合基金)
Guangdong Provincial Key Laboratory of Robotics and Intelligent Systems (Key Laboratory for Robotics and Intelligent Systems, Guangdong Province)
China Postdoctoral Science Foundation
GDPH | High-level Hospital Construction Project of Guangdong Provincial People's Hospital (High-level Hospital Construction Project)
Guangdong Provincial People's Hospital (GDPH)
GDSTC | Basic and Applied Basic Research Foundation of Guangdong Province (廣東省基礎與應用基礎研究專項資金)
ARTICLE ABSTRACT
DR has the potential to identify patients with high-risk colorectal cancer and predict the efficacy of adjuvant chemotherapy in patients with stage II colorectal cancer. Our findings support reporting DR types as additional pathologic parameters in clinical practice for more precise risk stratification.