crc-23-0013_fig2.png (548.35 kB)

FIGURE 2 from Deconstructing Olfactory Epithelium Developmental Pathways in Olfactory Neuroblastoma

figure

posted on 2023-06-06, 14:20 authored by John B. Finlay, Ralph Abi Hachem, David W. Jang, Nosayaba Osazuwa-Peters, Bradley J. Goldstein

Pseudodeconvolution of ONB bulk RNA-seq defines proportions of cell type–specific transcriptomics across low- and high-grade tumors. A, Stacked bar chart depicts predicted proportions of cell types in bulk tumors when mapped to control adult human olfactory mucosa using the deconvolution model. B, Statistical differences in selected ONB cellular composition, based on one-way ANOVA followed by post hoc Tukey test (*, P < 0.05; **, P < 0.01).

Funding

HHS | National Institutes of Health (NIH)

History

ARTICLE ABSTRACT

Our analyses provide a basis for additional research on olfactory neuroblastoma management, as well as identification of potential new prognostic markers.