Table S4 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

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posted on 2023-04-04, 01:46 authored by Alvaro G. Alvarado, Kaleab Tessema, Sree Deepthi Muthukrishnan, Mackenzie Sober, Riki Kawaguchi, Dan R. Laks, Aparna Bhaduri, Vivek Swarup, David A. Nathanson, Daniel H. Geschwind, Steven A. Goldman, Harley I. Kornblum

Normalized Enrichment Scores for each sample based on gene lists

Funding

UC President's Postdoctoral Fellowship

Dr. Miriam and Sheldon G. Adelson Medical Research Foundation (AMRF)

HHS | NIH | National Cancer Institute (NCI)

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ARTICLE ABSTRACT

Molecular classification of GBM has not yet resulted in the development of effective therapies. We have developed an integrative approach to identify molecular targets differentially utilized by individual tumors. This approach could lead to patient- and tumor-specific therapeutics.

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Keywords

Precision Medicine Tumor Heterogeneity CNS Cancers Gliomas, Glioblastomas Cell Cycle Signal transduction pathways Translational Research Genome Biology Comparative transcriptomics

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CC BY

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