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Supplementary Table from A Pan-Cancer Immunogenomic Atlas for Immune Checkpoint Blockade Immunotherapy

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posted on 2023-03-31, 05:06 authored by Jing Yang, Shilin Zhao, Jing Wang, Quanhu Sheng, Qi Liu, Yu Shyr
Supplementary Table from A Pan-Cancer Immunogenomic Atlas for Immune Checkpoint Blockade Immunotherapy

Funding

NCI

SPORE in Breast Cancer

National Cancer Institute

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Cancer Center Support Grant

National Cancer Institute

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ARTICLE ABSTRACT

The ability to identify robust genomic signatures that predict response to immune checkpoint blockade is restricted by limited sample sizes and ungeneralizable performance across cohorts. To address these challenges, we established Cancer-Immu (http://bioinfo.vanderbilt.edu/database/Cancer-Immu/), a comprehensive platform that integrates large-scale multidimensional omics data, including genetic, bulk, and single-cell transcriptomic, proteomic, and dynamic genomic profiles, with clinical phenotypes to explore consistent and rare immunogenomic connections. Currently Cancer-Immu has incorporated data for 3,652 samples for 16 cancer types. It provides easy access to immunogenomic data and empowers researchers to translate omics datasets into biological insights and clinical applications. Cancer-Immu is a comprehensive functional portal for unraveling immune-genomic connections to improve immune checkpoint blockade–based cancer immunotherapy.

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