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Supplementary Table 6 from ANO1 Reprograms Cholesterol Metabolism and the Tumor Microenvironment to Promote Cancer Metastasis

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posted on 2025-11-24, 23:04 authored by Chun-Miao Deng, Guo-Geng Zhang, Qin-Wen Liu, Jiao-Jiao Xu, Zhi-Chao Liu, Jing Yang, Tao-Yang Xu, Zhi-Gang Li, Fan Zhang, Bin Li
<p>Supplementary Table 6 shows DEGs of EC9706 overexpressing ANO1 and control cells</p>

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National Key Research and Development Program of China (NKPs)

National Natural Science Foundation of China (NSFC)

Key Laboratory of Guangdong Higher Education Institutes

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    DOI - Is supplement to ANO1 Reprograms Cholesterol Metabolism and the Tumor Microenvironment to Promote Cancer Metastasis

ARTICLE ABSTRACT

Metastatic cancer cells upregulate ANO1 to activate cell-intrinsic and -extrinsic mechanisms that alter cholesterol metabolism and stimulate fibroblasts, which can be targeted with ANO1 inhibitors to inhibit metastatic growth.See related commentary by Singh and Mehla, p. 1759

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    Cancer Research

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    Gastrointestinal CancersEsophageal cancerMetabolismMetabolic pathwaysOncogenes & Tumor SuppressorsOncogenesProgression, Invasion & MetastasisMetastasisSmall Molecule Agents

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