posted on 2023-05-08, 14:20authored byVinay Jain, Divyashri Baraniya, Doaa E. El-Hadedy, Tsute Chen, Michael Slifker, Fadhl Alakwaa, Kathy Q. Cai, Kumaraswamy N. Chitrala, Christopher Fundakowski, Nezar N. Al-Hebshi
Quantity and quality of the DNA and RNA extracts and the seqeuncing libraries.
Funding
HHS | NIH | National Institute of Dental and Craniofacial Research (NIDCR)
Dr. Cary. R. Klimen Oral Health Sciences Research Program Fund
History
ARTICLE ABSTRACT
Studies have shown that a distinct microbiome is associated with OSCC, but how the microbiome functions within the tumor interacts with the host cells remains unclear. By simultaneously characterizing the microbial and host transcriptomes in OSCC and control tissues, the study provides novel insights into microbiome-host interactions in OSCC which can be validated in future mechanistic studies.