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Related Article from The Ultimate in Cancer Chemoprevention: Cancer Vaccines
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posted on 2023-04-03, 19:21 authored by Mary L. DisisRelated Article from The Ultimate in Cancer Chemoprevention: Cancer Vaccines
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ARTICLE ABSTRACT
This perspective on Beatty et al. (beginning on page 438 in this issue of the journal) discusses the role of the immune system as nature's ultimate chemoprevention agent. A successful immune response to vaccination results in immunologic memory. In the case of a successful cancer-related response, antigen-specific T cells will be poised to destroy an aberrantly expressed protein even if the host is not exposed until years after the end of immunizations. After the abnormal cell is eradicated, T cells will lie in wait for the next exposure. The ability to develop effective cancer vaccines for prevention is fast becoming a reality as immunogenic aberrant proteins that drive malignant transformation are identified. Cancer Prev Res; 3(4); 406–9. ©2010 AACR.Usage metrics
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