American Association for Cancer Research
Browse

Related Article from The Origins and Implications of Intratumor Heterogeneity

Download (0.73 kB)
dataset
posted on 2023-04-03, 19:25 authored by Franziska Michor, Kornelia Polyak
Related Article from The Origins and Implications of Intratumor Heterogeneity

History

ARTICLE ABSTRACT

Human tumors often display startling intratumor heterogeneity in various features including histology, gene expression, genotype, and metastatic and proliferative potential. This phenotypic and genetic heterogeneity plays an important role in neoplasia, cancer progression, and therapeutic resistance. In this issue of the journal (beginning on page 1388), Merlo et al. report their use of molecular data from 239 patients with Barrett's esophagus to evaluate the propensity of major diversity indices for predicting progression to esophageal adenocarcinoma. This work helps elucidate the implications of molecular heterogeneity for the evolution of neoplasia. Cancer Prev Res; 3(11); 1361–4. ©2010 AACR.

Usage metrics

    Cancer Prevention Research

    Licence

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC