posted on 2023-03-31, 15:45authored byGuy T. Clifton, George E. Peoples
Related Article from Overcoming Cancer Immune Tolerance and Escape
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ARTICLE ABSTRACT
Although HER2/neu–targeted cancer vaccines have shown initial promise in the adjuvant setting, a therapeutic vaccine remains elusive due to the tumor escape mechanisms of established cancer. As described by Seavey et al. in this issue of CCR, a Listeria-delivered vaccine may help overcome immune tolerance, leading to an effective therapeutic vaccine.