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Related Article from Next-Generation Medicine: Combining BCR-ABL and Hedgehog-Targeted Therapies

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posted on 2023-03-31, 17:49 authored by Kim-Hien T. Dao, Jeffrey W. Tyner
Related Article from Next-Generation Medicine: Combining BCR-ABL and Hedgehog-Targeted Therapies

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ARTICLE ABSTRACT

Disease relapse remains a major cause of death in patients with BCR-ABL–positive leukemia despite advances in treatment with kinase inhibitors. Significant efforts are underway to target pathways that maintain leukemia stem cells. Targeting these pathways holds promise for definitive leukemia eradication or improvement of the effectiveness of currently available therapies. Clin Cancer Res; 19(6); 1309–11. ©2013 AACR.