American Association for Cancer Research
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Related Article from HER-2, Notch, and Breast Cancer Stem Cells: Targeting an Axis of Evil

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posted on 2023-03-31, 15:43 authored by Hasan Korkaya, Max S. Wicha
Related Article from HER-2, Notch, and Breast Cancer Stem Cells: Targeting an Axis of Evil

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ARTICLE ABSTRACT

Increasing evidence indicates that tumor-initiating (cancer stem) cells may contribute to treatment resistance and relapse, suggesting that improved clinical outcome will require effective targeting of this cell population. Recent studies suggest that the remarkable clinical efficacy of trastuzumab may relate to its ability to target cancer stem cell populations.