posted on 2023-03-31, 15:43authored byHasan Korkaya, Max S. Wicha
Related Article from HER-2, Notch, and Breast Cancer Stem Cells: Targeting an Axis of Evil
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ARTICLE ABSTRACT
Increasing evidence indicates that tumor-initiating (cancer stem) cells may contribute to treatment resistance and relapse, suggesting that improved clinical outcome will require effective targeting of this cell population. Recent studies suggest that the remarkable clinical efficacy of trastuzumab may relate to its ability to target cancer stem cell populations.