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Related Article from Dual PI3K/mTOR Inhibitors: Does p53 Modulate Response?

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posted on 2023-03-31, 17:14 authored by Oleksandr Ekshyyan, Arunkumar Anandharaj, Cherie-Ann O. Nathan
Related Article from Dual PI3K/mTOR Inhibitors: Does p53 Modulate Response?

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ARTICLE ABSTRACT

Head and neck squamous cell carcinomas have multiple genetic alterations that can influence clinical response to treatment. It is important to evaluate how distinct alterations affect response to targeted agents to identify a subset of patients who can benefit from therapy, improving survival and decreasing toxicity. Clin Cancer Res; 19(14); 3719–21. ©2013 AACR.

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    Clinical Cancer Research

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    Drug MechanismsCellular responses to anticancer drugsp53 and anticancer drug actionDrug TargetsProtein kinase & phosphatase drug targetsHead, Neck & Oral CancersOncogenes & Tumor Suppressorsp53Small Molecule Agents

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