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Related Article from CD137 as a Biomarker for Tumor-Reactive T Cells: Finding Gold in the Desert

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posted on 2023-03-31, 17:34 authored by Yuwen Zhu, Lieping Chen

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ARTICLE ABSTRACT

Although human cancer is often surrounded by immune cells, only a small number are tumor-reactive T cells that recognize the tumor antigens and are able to eliminate the cancer cells. Ye and colleagues now found that many of these tumor-reactive T cells are marked by expressing CD137, a T-cell costimulatory receptor. Clin Cancer Res; 20(1); 3–5. ©2013 AACR.